FTR 211 | Course Introduction and Application Information - Department of Physiotherapy and Rehabilitation

Course Name

Physiopathology

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
FTR 211	Fall	3	0	3	4

Prerequisites	None
Course Language	Turkish
Course Type	Required
Course Level	First Cycle
Mode of Delivery	face to face
Teaching Methods and Techniques of the Course	Discussion Q&A Lecture / Presentation
National Occupation Classification	-
Course Coordinator	Dr.Öğretim Üyesi Barış GÜRPINAR
Course Lecturer(s)	Öğr.Gör.Dr. EYLÜL ALTINAĞIZ
Assistant(s)	Arş.Gör. MUSTAFA TAHSİN ÖZER

Course Objectives	The aim of this course is to learn the etiopathogenesis and pathophysiology of diseases, the basic morphological changes that occur during diseases.
Learning Outcomes	The students who succeeded in this course; Describe the mechanisms of cell injury, adaptation, and tissue repair. Explain the general characteristics, types, systemic effects, and morphological findings of inflammation, as well as the characteristics, etiology, molecular basis, and nomenclature of cancer. Explain the pathogenesis and morphological findings of hemodynamic disorders, thromboembolic diseases, infarction, and shock. Describe the pathogenesis and morphological findings of infectious and genetic diseases, as well as environmental and nutritional disorders. List the pathogenesis and morphological findings of hypersensitivity and immune system diseases. Discuss the pathogenesis and morphological findings of diseases originating in the central and peripheral nervous systems. Discuss the etiology, pathogenesis and morphological findings of muscle, bone, soft tissue, joint and cardiovascular system diseases.
Course Description	This course includes cellular response to stress, cell injury and death, acute and chronic inflammation, tissue repair and wound healing, hemodynamic disorders, thromboembolic diseases, infarction, shock, neoplasia, hypersensitivity reactions and immune system diseases, environmental pathology and nutritional disorders, and nerve, muscle, bone, soft tissue, joint diseases and cardiovascular system diseases.
Related Sustainable Development Goals

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Management Skills Courses
	Transferable Skill Courses

Week	Subjects	Related Preparation
1	Course introduction, introduction to pathology,cell structure, and response to cell injury	1. Yaman Örs, Patoloji ve Tıptaki Yeri, sayfa 1-2, Temel Patoloji, Mocan Kuzey G, Özdamar Ş.O, Zergeroğlu S., Güneş Kitabevi, 2007,ISBN: 975-277-104-1 2. Richard N.Mitchell, Hücre hasarı, hücre ölümü ve adaptasyonlar, Bölüm 1, sayfa: 1-5, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6
2	Functions of the cell, cell death, and acute inflammation	1. Richard N.Mitchell, Hücre hasarı, hücre ölümü ve adaptasyonlar, Bölüm 1, sayfa: 6-28, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6
3	Formation of inflammation, chronic inflammation, wound healing and regeneration	1. Richard N.Mitchell, İnflamasyon ve onarım, Bölüm 2, sayfa: 58-73, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6
4	Functions of blood, hemodynamic and thrombotic disorders, cardiovascular system functions and physiopathology	1. Richard N.Mitchell, Hemodinamik bozukluklar, Tromboembolizm ve Şok, Bölüm 3, sayfa: 75-98, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6 2. Ganong'un Tıbbi Fizyolojisi, Brooks, Barrett, Barman, Boitano, Çeviri Editörü: Ümmühan İşoğlu Alkaç, Numan Ermutlu, 2018. 519-601
5	Functions of the immune system, infectious and genetic diseases	1. Alexander J. McAdam, Arlene H. Sharpe, Enfeksiyon Hastalıklarının Genel Patolojisi , Bölüm 8, sayfa: 309-326, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6
6	Hypersensitivity and immune system disorders, Immunopathology functions of the endocrine system	1. Richard N.Mitchell, İmmun system hastalıkları, Bölüm 4, sayfa: 99-160, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6 2. Hall, John E., and Michael E. Hall. Guyton ve Hall Medikal Fizyoloji. Elsevier Health Sciences, 2020. Bölüm 35
7	Environmental pathology and nutritional disorders, gastrointestinal system functions, endocrine and gastrointestinal system pathophysiology	1. Alexander J. McAdam, Arlene H. Sharpe, Çevresel ve Beslenme ile İlgili Hastalıklar, Bölüm 7, sayfa: 269-306, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6 2. Ganong'un Tıbbi Fizyolojisi, Brooks, Barrett, Barman, Boitano, Çeviri Editörü: Ümmühan İşoğlu Alkaç, Numan Ermutlu, 2018. 297-377
8	Functions of the nervous and sensory systems, neoplasia	1. Alexander J. McAdam, Arlene H. Sharpe, Neoplazi , Bölüm 5, sayfa: 162-214, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri , 2014, ISBN: 978-605-335-002-6
9	Midterm exam
10	Functions of the nervous and sensory systems, nervous system pathology	1. Peter Pytel, Santral sinir sistemi, Bölüm 22, sayfa: 811-850, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6 2. Andrew E. Rosenber, Periferik sinirler ve kaslar, Bölüm 21, sayfa:797- 810, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6
11	Structure and functions of the musculoskeletal system and bone tissue pathology	1. Anirban Maitra, Kemikler, eklemler ve yumuşak doku tümörleri, Bölüm 20, sayfa: 765-810, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6
12	Structure and functions of the musculoskeletal system, muscle tissue pathology, musculoskeletal system pathophysiology	1. Andrew E. Rosenber, Periferik sinirler ve kaslar, Bölüm 21, sayfa:797- 810, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6 2. Ganong'un Tıbbi Fizyolojisi, Brooks, Barrett, Barman, Boitano, Çeviri Editörü: Ümmühan İşoğlu Alkaç, Numan Ermutlu, 2018. 97-135
13	Soft tissue pathology, joint pathology	1. Anirban Maitra, Kemikler, eklemler ve yumuşak doku tümörleri, Bölüm 20, sayfa: 765-810, Robbins Temel Patoloji, Kumar, Abbas, Aster, dokuzuncu Basım , Nobel Tıp Kitabevleri, 2014, ISBN: 978-605-335-002-6
14	Artificial intelligence in pathology
15	Semester review
16	Final Exam

Course Notes/Textbooks

Kumar, Abbas, Aster, Robbins Temel Patoloji, Dokuzuncu Basım, 2014, Nobel Tıp Kitabevleri, , ISBN: 978-605-335-002-6
Gamze Mocan Kuzey, Şükrü Oğuz Özdamar, Sema Zergeroğlu, Temel Patoloji, 2007, Güneş Kitabevi, ISBN: 978-605-335-002-6
Ganong'un Tıbbi Fizyolojisi, Brooks, Barrett, Barman, Boitano, Çeviri Editörü: Ümmühan İşoğlu Alkaç, Numan Ermutlu, 2018 ISBN: 978-0071825108
Hall, John E., and Michael E. Hall. Guyton ve Hall Medikal Fizyoloji. Elsevier Health Sciences, 2020. ISBN: 978-0323-67280-1

Suggested Readings/Materials

Carie A. Braun, Cindy M. Anderson, Pathophysiology “A clinical approach”, second edition, 2011, Lippincott Williams & Wilkins,ISBN: 978-1-60547-304-8
Gary D. Hammer ,Stephen J.McPhee, Pathophysiology of disease “An Introduction to Clinical medicine” seventh edition, 2014, Lange,ISBN: 978-0-07-180600-8

Semester Activities	Number	Weigthing
Participation	1	20
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
Presentation / Jury
Project
Seminar / Workshop
Oral Exams
Midterm	1	30
Final Exam	1	50
Total

Weighting of Semester Activities on the Final Grade	2	50
Weighting of End-of-Semester Activities on the Final Grade	1	50
Total

Semester Activities	Number	Duration (Hours)	Workload
Theoretical Course Hours (Including exam week: 16 x total hours)	16	4	64
Laboratory / Application Hours (Including exam week: '.16.' x total hours)	16		0
Study Hours Out of Class			0
Field Work			0
Quizzes / Studio Critiques			0
Portfolio			0
Homework / Assignments			0
Presentation / Jury			0
Project			0
Seminar / Workshop			0
Oral Exam			0
Midterms	1	10	10
Final Exam	1	16	16
		Total	90

#	Program Competencies/Outcomes	* Contribution Level
#	Program Competencies/Outcomes	1	2	3	4	5
1	To be able to define issues, and conduct evaluation and planning in health, disease and disability, using theoretical and applied concepts and principles of Physiotherapy and Rehabilitation.	-	X	-	-	-
2	To be able to demonstrate the analytical and practical skills to identify, formulate and to resolve issues affecting health; to be able to specify and apply the evidence-based practices in clinical decision-making.	-	-	X	-	-
3	To be able to effectively use devices, tools and equipment, appropriate treatment techniques and modalities, up-to-date informatics and rehabilitation technologies in the field of Physiotherapy and Rehabilitation.	-	-	-	-	-
4	To be able to record and collect data, analyze, interpret, and present results in health sciences.	-	-	-	-	-
5	To be able to take responsibility, and demonstrate efficient working and management skills autonomously, as an individual, and as part of a healthcare team.	-	X	-	-	-
6	To be able to adopt the principle of lifelong learning; critically evaluate the nature, source, limits, accuracy, reliability and validity of information; access up-to-date scientific and technological information and practices.	-	X	-	-	-
7	To be able to communicate with, and convey information to the individuals/groups regardless of their sociocultural background, education level, age or disability status.	-	-	-	-	-
8	To be able to understand and apply legal rights, regulations and responsibilities regarding the physiotherapy profession and practices; to participate in academic, professional, regional, and global networks, and to utilize these networks efficiently.	-	-	-	-	-
9	To acquire the ability to perform, record and archive Physiotherapy and Rehabilitation applications according to the principles of healthcare quality, patient and occupational safety, professional deontology and ethics.	-	-	-	-	-
10	To be able to contribute to the public health promotion via developing novel approaches to meet the diverse and changing needs of society, and to develop health policies in the field of Physiotherapy and Rehabilitation.	-	-	-	-	-
11	To be able to communicate with patients and healthcare team and perform clinical applications in a foreign language ("European Language Portfolio Global Scale", Level B1)	-	-	-	-	-